Jonathan Bramson, PhD, is the Vice Dean, Research for the Faculty of Health Sciences and a Professor in the Department of Medicine at McMaster University. He holds the John Bienenstock Chair in Molecular Medicine. His research is focused on the use of cells as drugs. Specifically, his lab is developing methods to manufacture white blood cell “drugs” that attack cancer. To optimize the anti-tumor activity of these white blood cell drugs, his research team is using a combination of genetic engineering, synthetic biology, and chemical biology approaches to re-wire relevant signaling pathways within white blood cells to bolster their anti-tumor potency.
Together with Dr. Christopher Helsen, Dr. Bramson developed the T cell antigen coupler (TAC) receptor in 2014 and founded Triumvira Immunologics in 2015. Dr. Bramson served as the CSO for Triumvira from 2015 – 2020 and currently serves as the Chair of the Scientific Advisory Committee.